Gck | glucokinase
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Mortality/aging
15 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
7Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Gckem1(IMPC)H | homozygote | Early adult | N/A * | ||
| impaired glucose tolerance | 1 supporting dataset | Gckem1(IMPC)H | heterozygote | Early adult | 7.48x10-14 | ||
| increased circulating fructosamine level | 1 supporting dataset | Gckem1(IMPC)H | heterozygote | Early adult | 2.33x10-10 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Gckem1(IMPC)H | heterozygote | Early adult | 3.5x10-9 | ||
| increased circulating glucose level | 1 supporting dataset | Gckem1(IMPC)H | heterozygote | Early adult | 8.71x10-14 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Gckem1(IMPC)H | heterozygote | Early adult | 4.5x10-17 |
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External links
No external links available for Gck.
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| Gckem1(IMPC)H | Exon Deletion | | mouse |
| Gckem2(IMPC)H | Exon Deletion | | mouse |
| Gcktm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |