Rhd | Rh blood group, D antigen

GeneMGI:1202882Synonyms: Rhced, Rhl1, +1 more

Physiological systems

21 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Hematopoietic system Behavior/neurological

17 No significant impact

3 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:10Significant phenotypes
5Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

increased exploration in new environment1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult5.94x10-9 
decreased mean corpuscular volume1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult1.22x10-7 
decreased circulating free fatty acids level1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult1.31x10-5 
decreased circulating cholesterol level1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult1.74x10-5 
decreased circulating HDL cholesterol level1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult6.09x10-6 
decreased mean corpuscular hemoglobin1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult8.43x10-5 
decreased mean corpuscular hemoglobin concentration1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult1.23x10-14 
decreased circulating alkaline phosphatase level1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult2.01x10-5 
abnormal skin condition1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult4.39x10-6 
decreased hemoglobin content1 supporting datasetRhdtm1e(EUCOMM)WtsihomozygoteEarly adult1.11x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Rhdtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Rhdtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Rhdtm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
mouse

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