Sec61g | SEC61 translocon subunit gamma

GeneMGI:1202066

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Integument Behavior/neurological Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



tremors	1 supporting dataset	Sec61g^em1(IMPC)J	heterozygote	Early adult	6.96x10^-5
preweaning lethality, complete penetrance	2 supporting datasets	Sec61g^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal coat/ hair morphology	1 supporting dataset	Sec61g^em1(IMPC)J	heterozygote	Early adult	3.22x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sec61g.

Associated images

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Histopathology

There is no histopathology data found for Sec61g.

IMPC related publications

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External links

No external links available for Sec61g.

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*Sec61g^em1(IMPC)J*	Whole-gene deletion	‌	mouse
*Sec61g^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Sec61g^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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