Otog | otogelin

GeneMGI:1202064Synonyms: Otgn

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Integument Hearing/vestibular/ear Mortality/aging

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal auditory brainstem response5 supporting datasetsOtogem1(IMPC)JhomozygoteEarly adult6.54x10-13 
abnormal vibrissa morphology1 supporting datasetOtogem1(IMPC)JhomozygoteEarly adult1.07x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetOtogem1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Otogem1(IMPC)JExon Deletionmouse
Otogtm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Otogtm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Otogtm1e(KOMP)MbpTargeted, non-conditional allelees cell
Otogtm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Otogtm2a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Otogtm2e(KOMP)MbpTargeted, non-conditional allelees cell

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