Brms1l | breast cancer metastasis-suppressor 1-like

GeneMGI:1196337Synonyms: D12Ertd407e, BRMS1, +1 more

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Adipose tissue Behavior/neurological Skeleton

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal bone structure1 supporting datasetBrms1lem1(IMPC)JhomozygoteEarly adult4.05x10-6 
decreased bone mineral density1 supporting datasetBrms1lem1(IMPC)JhomozygoteEarly adult1.04x10-5 
decreased bone mineral content2 supporting datasetsBrms1lem1(IMPC)JhomozygoteEarly adult7.99x10-7 
increased total body fat amount1 supporting datasetBrms1lem1(IMPC)JhomozygoteEarly adult6.43x10-5 
increased aggression1 supporting datasetBrms1lem1(IMPC)JheterozygoteEarly adult2.21x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Brms1lem1(IMPC)JExon Deletionmouse
Brms1ltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Brms1ltm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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