Fadd | Fas associated via death domain
Physiological systems
19 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Reproductive system Adipose tissue Embryo Growth/size/body region Nervous system Mortality/aging
13 No significant impact
5 Not tested
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:41Adult tissues
29Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Faddtm1e.1(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| increased total body fat amount | 1 supporting dataset | Faddtm1e.1(KOMP)Wtsi | heterozygote | Early adult | 7.18x10-5 | ||
| decreased lean body mass | 1 supporting dataset | Faddtm1e.1(KOMP)Wtsi | heterozygote | Early adult | 9.71x10-12 | ||
| abnormal neural tube closure | 1 supporting dataset | Faddtm1e.1(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| abnormal uterus morphology | 1 supporting dataset | Faddtm1e.1(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Faddtm1e.1(KOMP)Wtsi | homozygote | E9.5 | N/A * |
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External links
No external links available for Fadd.
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