Ncs1 | neuronal calcium sensor 1

GeneMGI:109166Synonyms: NCS-1, A730032G13Rik, +2 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Behavior/neurological Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased total retina thickness	1 supporting dataset	Ncs1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.37x10^-5
abnormal cornea morphology	1 supporting dataset	Ncs1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.82x10^-6
decreased grip strength	2 supporting datasets	Ncs1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.42x10^-6
increased circulating phosphate level	1 supporting dataset	Ncs1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	5.97x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Ncs1^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ncs1.

Associated images

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Histopathology

There is no histopathology data found for Ncs1.

IMPC related publications

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External links

No external links available for Ncs1.

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*Ncs1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ncs1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Ncs1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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