Bag1 | BCL2-associated athanogene 1

GeneMGI:108047Synonyms: Rap46

Physiological systems

20 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Hematopoietic system Cardiovascular system

18 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased hemoglobin content1 supporting datasetBag1tm1a(EUCOMM)HmguhomozygoteEarly adult3.92x10-5 
decreased mean corpuscular volume1 supporting datasetBag1tm1a(EUCOMM)HmguhomozygoteEarly adult1.71x10-5 
decreased heart weight1 supporting datasetBag1tm1a(EUCOMM)HmguhomozygoteEarly adult8.72x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bag1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Bag1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Bag1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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