Rock1 | Rho-associated coiled-coil containing protein kinase 1

GeneMGI:107927Synonyms: Rock-I, 1110055K06Rik

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

51Embryo tissues

Phenotypes

Phy. System:

Life Stage:



edema	1 supporting dataset	Rock1^{tm1b(NCOM)Mfgc}	homozygote	E15.5	N/A ^*
preweaning lethality, incomplete penetrance	3 supporting datasets	Rock1^{tm1b(NCOM)Mfgc}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rock1.

Associated images

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Histopathology

There is no histopathology data found for Rock1.

IMPC related publications

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External links

No external links available for Rock1.

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*Rock1^{tm1a(NCOM)Mfgc}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rock1^{tm1b(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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