Dusp1 | dual specificity phosphatase 1

GeneMGI:105120Synonyms: 3CH134, erp, +3 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Growth/size/body region Hematopoietic system

16 No significant impact

5 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

thrombocytosis1 supporting datasetDusp1tm1(KOMP)WtsihomozygoteEarly adult8.5x10-5 
decreased body weight2 supporting datasetsDusp1tm1(KOMP)WtsihomozygoteEarly adult1.34x10-5 
increased circulating magnesium level1 supporting datasetDusp1tm1(KOMP)WtsihomozygoteEarly adult6.47x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dusp1tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse

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