Mxd4 | Max dimerization protein 4

GeneMGI:104991Synonyms: bHLHc12, Mad4, +1 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system Cardiovascular system

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating alkaline phosphatase level1 supporting datasetMxd4em1(IMPC)JhomozygoteEarly adult9.25x10-20 
increased circulating calcium level1 supporting datasetMxd4em1(IMPC)JhomozygoteEarly adult4.55x10-5 
prolonged QRS complex duration1 supporting datasetMxd4em1(IMPC)JhomozygoteEarly adult2.04x10-5 
increased leukocyte cell number1 supporting datasetMxd4em1(IMPC)JhomozygoteEarly adult1.05x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mxd4em1(IMPC)JExon Deletionmouse
Mxd4tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Mxd4tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Mxd4tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Mxd4tm2e(KOMP)WtsiTargeted, non-conditional allelees cell
Mxd4tm45050(L1L2_gt2)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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