Il12rb1 | interleukin 12 receptor, beta 1

GeneMGI:104579Synonyms: CD212, IL-12R[b]

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Integument Adipose tissue Vision/eye Hematopoietic system

14 No significant impact

6 Not tested

Gene metrics:5Significant phenotypes
3Associated diseases
Expression examined in:51Adult tissues
0Embryo tissues

Phenotypes

abnormal skin coloration1 supporting datasetIl12rb1tm1b(KOMP)WtsihomozygoteEarly adult2.54x10-5 
decreased hemoglobin content1 supporting datasetIl12rb1tm1b(KOMP)WtsihomozygoteEarly adult1.22x10-6 
abnormal eye posterior chamber depth1 supporting datasetIl12rb1tm1b(KOMP)WtsihomozygoteEarly adult2.19x10-5 
decreased total body fat amount1 supporting datasetIl12rb1tm1b(KOMP)WtsihomozygoteEarly adult4.34x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Il12rb1tm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Il12rb1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Il12rb1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Il12rb1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Il12rb1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Il12rb1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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