Lmo1 | LIM domain only 1

GeneMGI:102812Synonyms: Rbtn1, Ttg1, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Nervous system Vision/eye Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity3 supporting datasetsLmo1tm1b(KOMP)MbphomozygoteEarly adult1.98x10-7 
decreased prepulse inhibition1 supporting datasetLmo1tm1b(KOMP)MbphomozygoteEarly adult8.42x10-7 
abnormal behavior1 supporting datasetLmo1tm1b(KOMP)MbphomozygoteEarly adult3.82x10-5 
decreased thigmotaxis2 supporting datasetsLmo1tm1b(KOMP)MbphomozygoteEarly adult5.31x10-6 
decreased vertical activity1 supporting datasetLmo1tm1b(KOMP)MbphomozygoteEarly adult5.47x10-12 
decreased anxiety-related response1 supporting datasetLmo1tm1b(KOMP)MbphomozygoteEarly adult4.05x10-6 
abnormal retina morphology1 supporting datasetLmo1tm1b(KOMP)MbphomozygoteEarly adult1.77x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lmo1tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lmo1tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Lmo1tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell

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