Workshops

The second part of the IMPC Cardio and Metabolism workshop was held on 8 January 2025! Professor Deborah Henderson from the University of Newcastle, UK talked about Congenital Heart Defects (CHD), which are considered to have a significant genetic component. Professor John Banks from Harvard Medical School, USA discussed the efforts to establish global standards for metabolism research with indirect calorimetry.

This course is designed for anyone interested in learning how to access IMPC data using Python. It will provide you with the necessary skills to navigate and utilise the data effectively. However, basic Python programming skills are required so an introductory Python course is recommended. If you’re new to IMPC or want to explore its resources further, we suggest starting with our course The International Mouse Phenotyping Consortium: Finding phenotypes for your gene of interest.

The IMPC Data API Workshop was aimed to enable people to construct simple Solr API queries to obtain IMPC data based on an understanding of the structure of IMPC data, specifically how knowledge of IMPReSS can be used together with the Solr API to extract datasets from IMPC. After the course people should be able to automate tasks that could be accomplished through the website by looking manually at multiple web pages.

Emerging technologies now enable identification and analysis of the pathophysiological consequences of genetic disruptions in these genes in mice. This workshop explores opportunities to use IMPC mutant mice to investigate genetic mechanisms of anosmia and dysgeusia and the broader implication on neurodegenerative disease and cognitive decline in humans.

Workshop on major international initiatives to promote the use of Home Cage Monitoring (HCM) as an important tool in behavioural studies and discuss the evaluation of current opportunities and feasibility of HCM as a novel and complementary tool in behavioral phenotyping with particular attention to its feasibility in terms of data/video handling and analysis.

The IMPC generates single gene knockout mice with an emphasis on genes that have yet to be studied. Mutants and wild type mice are tested using common phenotyping protocols and the results are publicly available as data and mouse strains https://www.mousephenotype.org for the scientific community to use. In this presentation, Dr. Kevin Peterson from the Jackson Laboratory explains how IMPC knockout mouse strains are generated and phenotyped.