A Fear Conditioning phenotypic assay was performed on 561 mice. The charts show the results of measuring Cue Baseline % Freezing Time in 5 female, 8 male mutants compared to 290 female, 258 male controls. The mutants are for the Tafa2em1(IMPC)H allele.
increased freezing behavior
Loading data
P-values equal or lower to 10-4 (P < 0.0001) are marked as significant.
| Cue Baseline % Freezing Time | MRC Harwell | Tafa2em1(IMPC)H | homozygote | Early adult | H-FAM19A2-DEL517-EM1-B6N | 1.75x10-8 | 1.41x10-1 | 1.49x10-1 | |
Tafa2 data charts
Cue Baseline % Freezing TimeExperiments performed
Associated phenotype
Zygosity
homozygote
Testing protocol
Measured value
Cue Baseline % Freezing Time
Testing environment
Lab conditions and equipment
Life stage
Early adult
Background Strain
involves: C57BL/6NTac
Phenotyping center
MRC Harwell
* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.
Cue Baseline % Freezing Time / Box plot
Cue Baseline % Freezing Time / Scatter plot
Results of statistical analysis
Genotype P value
1.49x10-1
Genotype*Female P value
1.41x10-1
Genotype*Male P value
1.75x10-8
Classification
Overally insignificant [level = 1e-04 , pvalue = 0.149122238495637 ]; but with phenotype threshold value 1e-04 - males only
Summary statistics of all data in the dataset
Statistical method
| Batch effect significant | true |
| Variance significant | true |
| Genotype*Sex interaction effect p value | 1.49x10-1 |
| Genotype parameter estimate | 4.952 |
| Genotype standard error estimate | 8.501 |
| Genotype Effect P Value | 1.49x10-1 |
| Sex Parameter Estimate | 4.952 |
| Sex Standard Error Estimate | 2.064 |
| Sex Effect P Value | 1.49x10-1 |
| Intercept Estimate | 26.039 |
| Intercept Estimate Standard Error | 1.457 |
| Sex Male KO P Value | 1.49x10-1 |
| Sex Female KO P Value | 1.49x10-1 |
| WT Residuals Normality Tests | 1.28x10-5 |
| KO Residuals Normality Tests | 5.71x10-2 |
Statistical analysis API access
Experimental data download
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