increased lymphocyte cell number

Loading data

P-values equal or lower to 10^-4 (P < 0.0001) are marked as significant.



Lymphocyte cell count	MARC	Etaa1^{em1(IMPC)Marc}	homozygote		Early adult	Etaa1_cas9_del22				2.05x10^-2	1.77x10^-4	4.6x10^-6

Etaa1 data charts

Lymphocyte cell count

Combination tested with the lowest p-value of 4.6x10^-6

Experiments performed

A Hematology phenotypic assay was performed on 937 mice. The charts show the results of measuring Lymphocyte cell count in 7 female, 7 male mutants compared to 473 female, 450 male controls. The mutants are for the Etaa1^{em1(IMPC)Marc} allele.

Associated phenotype

increased lymphocyte cell number

Zygosity

homozygote

Testing protocol

Hematology

Measured value

Lymphocyte cell count

Testing environment

Lab conditions and equipment

Life stage

Early adult

Background Strain

involves: C57BL/6N

Phenotyping center

MARC

* The high throughput nature of the IMPC means that large control sample sizes may accumulate over a long period of time. See the animal welfare guidelines for more information.

Lymphocyte cell count / Box plot

Lymphocyte cell count / Scatter plot

Results of statistical analysis

Genotype P value

4.6x10^-6

Genotype*Female P value

1.77x10^-4

Genotype*Male P value

2.05x10^-2

Classification

With phenotype threshold value 1e-04 - both sexes equally

Summary statistics of all data in the dataset

Statistical method



Batch effect significant	true
Variance significant	true
Genotype*Sex interaction effect p value	4.6x10^-6
Genotype parameter estimate	N/A
Genotype standard error estimate	0.349
Genotype Effect P Value	4.6x10^-6
Sex Parameter Estimate	N/A
Sex Standard Error Estimate	N/A
Sex Effect P Value	4.6x10^-6
Intercept Estimate	3.066
Intercept Estimate Standard Error	0.099
Sex Male KO P Value	4.6x10^-6
Sex Female KO P Value	4.6x10^-6
WT Residuals Normality Tests	4.26x10^-15
KO Residuals Normality Tests	1.93x10^-1