Phenotype: decreased CD5-positive Ly6C-positive T cell number

Definition
reduction in the number of CD5-positive T cells expressing the memory marker Ly6C
Synonyms
reduced CD5-positive Ly6C-positive T cell number
0%
of tested genes
0
significant genes
0
tested genes

IMPC Gene variants with decreased CD5-positive Ly6C-positive T cell number

Total number of significant genotype-phenotype associations: 5

Gene / Allele Zygosity Sex Life Stage Phenotype Parameter Phenotyping
Center
P Value
Ube3c
Ube3ctm1b(EUCOMM)Hmgu
HOM Early adult decreased CD5-positive Ly6C-positive T cell number T Subset
Immunophenotyping
HMGU
IMPC
1.54×10-07
Pepd
Pepdtm1b(KOMP)Wtsi
HOM Late adult decreased CD5-positive Ly6C-positive T cell number T Subset
Immunophenotyping
HMGU
IMPC
3.92×10-06
Nub1
Nub1tm1b(EUCOMM)Hmgu
HOM Early adult decreased CD5-positive Ly6C-positive T cell number T Subset
Immunophenotyping
CCP-IMG
IMPC
6.49×10-06
Pdgfc
Pdgfctm1b(EUCOMM)Hmgu
HET Late adult decreased CD5-positive Ly6C-positive T cell number T Subset
Immunophenotyping
HMGU
IMPC
4.65×10-05

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 The way we measure

 Phenotype associations stats

0.39% of tested genes with null mutations on a B6N genetic background have a phenotype association to decreased CD5-positive Ly6C-positive T cell number (4/1027)

1.64% females (1/61) 6.45% males (4/62)

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