Ighmbp2 | immunoglobulin mu DNA binding protein 2

GeneMGI:99954Synonyms: Smbp-2, RIPE3b1, +6 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Integument Growth/size/body region Skeleton Mortality/aging Renal/urinary system

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased bone mineral content	1 supporting dataset	Ighmbp2^em1(IMPC)Tcp	heterozygote	Early adult	5.36x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Ighmbp2^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal skin morphology	1 supporting dataset	Ighmbp2^em1(IMPC)Tcp	heterozygote	Late adult	N/A ^*
enlarged kidney	1 supporting dataset	Ighmbp2^em1(IMPC)Tcp	heterozygote	Late adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ighmbp2.

Associated images

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Histopathology

There is no histopathology data found for Ighmbp2.

IMPC related publications

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External links

No external links available for Ighmbp2.

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*Ighmbp2^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Ighmbp2^{tm46207(L1L2_gt1)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes