Creb3 | cAMP responsive element binding protein 3

GeneMGI:99946Synonyms: LZIP-2, Luman, +2 more

Physiological systems

22 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Reproductive system Growth/size/body region Behavior/neurological Mortality/aging

18 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

58Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, incomplete penetrance	3 supporting datasets	Creb3^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Creb3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*
hyperactivity	1 supporting dataset	Creb3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	9.82x10^-7
decreased body length	1 supporting dataset	Creb3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.26x10^-5
abnormal epididymis morphology	1 supporting dataset	Creb3^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Creb3.

Associated images

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Histopathology

There is no histopathology data found for Creb3.

IMPC related publications

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External links

No external links available for Creb3.

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*Creb3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Creb3^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Creb3^{tm234372(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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