Rab23 | RAB23, member RAS oncogene family
GeneMGI:99833
Physiological systems
19 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Hematopoietic system Skeleton Mortality/aging
14 No significant impact
5 Not tested
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| decreased lean body mass | 1 supporting dataset | Rab23tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.78x10-5 | ||
| increased circulating alanine transaminase level | 1 supporting dataset | Rab23tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.6x10-7 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Rab23tm1b(EUCOMM)Wtsi | homozygote | Early adult | N/A * | ||
| increased circulating aspartate transaminase level | 1 supporting dataset | Rab23tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 2.82x10-5 | ||
| increased mean platelet volume | 1 supporting dataset | Rab23tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 1.33x10-5 | ||
| decreased bone mineral content | 1 supporting dataset | Rab23tm1b(EUCOMM)Wtsi | heterozygote | Early adult | 3.2x10-5 |
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External links
No external links available for Rab23.
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| Rab23tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Rab23tm1b(EUCOMM)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Rab23tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |