Slc7a2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

GeneMGI:99828Synonyms: Atrc2, Cat2, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Hematopoietic system Skeleton

14 No significant impact

6 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
0Embryo tissues

Phenotypes

long tibia1 supporting datasetSlc7a2tm1b(EUCOMM)HmguhomozygoteEarly adult3.59x10-7 
increased mean corpuscular volume1 supporting datasetSlc7a2tm1b(EUCOMM)HmguhomozygoteLate adult3.52x10-9 
increased circulating iron level1 supporting datasetSlc7a2tm1b(EUCOMM)HmguhomozygoteLate adult2.99x10-10 
decreased circulating fructosamine level1 supporting datasetSlc7a2tm1b(EUCOMM)HmguhomozygoteLate adult8.03x10-6 
increased blood urea nitrogen level1 supporting datasetSlc7a2tm1b(EUCOMM)HmguhomozygoteLate adult2.14x10-6 
increased circulating cholesterol level1 supporting datasetSlc7a2tm1b(EUCOMM)HmguhomozygoteEarly adult5.75x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc7a2tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Slc7a2tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Slc7a2tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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