Rasgrf1 | RAS protein-specific guanine nucleotide-releasing factor 1

GeneMGI:99694Synonyms: CDC25, Grfbeta, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Growth/size/body region Behavior/neurological

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased lean body mass	1 supporting dataset	Rasgrf1^tm1bNarl	homozygote	Early adult	4.63x10^-5
hyperactivity	2 supporting datasets	Rasgrf1^tm1bNarl	homozygote	Early adult	2.94x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rasgrf1.

Associated images

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Histopathology

There is no histopathology data found for Rasgrf1.

IMPC related publications

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External links

No external links available for Rasgrf1.

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*Rasgrf1^tm1aNarl*	KO first allele (reporter-tagged insertion with conditional potential)	‌	ES Cell mouse
*Rasgrf1^tm1bNarl*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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