Adcy3 | adenylate cyclase 3

GeneMGI:99675Synonyms: AC3, ACIII

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Adipose tissue Growth/size/body region Hematopoietic system Mortality/aging

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased lean body mass	1 supporting dataset	Adcy3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.66x10^-5
increased hemoglobin content	1 supporting dataset	Adcy3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.77x10^-5
increased total body fat amount	1 supporting dataset	Adcy3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	8.49x10^-5
increased hematocrit	1 supporting dataset	Adcy3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.74x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Adcy3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Adcy3.

Associated images

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Histopathology

There is no histopathology data found for Adcy3.

IMPC related publications

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External links

No external links available for Adcy3.

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*Adcy3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Adcy3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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