Siglec1 | sialic acid binding Ig-like lectin 1, sialoadhesin

GeneMGI:99668Synonyms: CD169, Siglec-1, +1 more

Physiological systems

21 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Respiratory system Renal/urinary system

18 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased kidney weight	2 supporting datasets	Siglec1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	5.73x10^-7
increased lung weight	1 supporting dataset	Siglec1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.97x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Siglec1.

Associated images

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Histopathology

There is no histopathology data found for Siglec1.

IMPC related publications

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External links

No external links available for Siglec1.

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*Siglec1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Siglec1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Siglec1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Siglec1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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