Prdm1 | PR domain containing 1, with ZNF domain

GeneMGI:99655Synonyms: Blimp-1, b2b1765Clo, +2 more

Physiological systems

16 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Mortality/aging Cardiovascular system

12 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal heart morphology	1 supporting dataset	Prdm1^em1(IMPC)Bay	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Prdm1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Prdm1^em1(IMPC)Bay	heterozygote	E12.5	N/A ^*
embryonic lethality prior to tooth bud stage	1 supporting dataset	Prdm1^em1(IMPC)Bay	homozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Prdm1.

Associated images

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Histopathology

There is no histopathology data found for Prdm1.

IMPC related publications

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External links

No external links available for Prdm1.

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*Prdm1^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Prdm1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Prdm1^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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