Abca1 | ATP-binding cassette, sub-family A member 1
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Vision/eye Behavior/neurological Mortality/aging
15 No significant impact
4 Not tested
Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues
| unresponsive to tactile stimuli | 1 supporting dataset | Abca1tm1b(EUCOMM)Hmgu | homozygote | E18.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Abca1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| unresponsive to tactile stimuli | 1 supporting dataset | Abca1tm1b(EUCOMM)Hmgu | heterozygote | E18.5 | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Abca1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.14x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Abca1tm1b(EUCOMM)Hmgu | homozygote | E18.5 | N/A * |
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External links
No external links available for Abca1.
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| Abca1tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Abca1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Abca1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Abca1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |
| Abca1tm398(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Abca1tm398(L1L2_gt0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
| Abca1tm398(L1L2_st0) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |