Abca2 | ATP-binding cassette, sub-family A member 2

GeneMGI:99606Synonyms: D2H0S1474E, Abc2

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Behavior/neurological Skeleton

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity8 supporting datasetsAbca2em1(IMPC)JhomozygoteEarly adult2.34x10-12 
decreased grip strength2 supporting datasetsAbca2em1(IMPC)JhomozygoteEarly adult1.48x10-5 
abnormal coat/ hair morphology1 supporting datasetAbca2em1(IMPC)JhomozygoteEarly adult2.21x10-5 
increased exploration in new environment1 supporting datasetAbca2em1(IMPC)JhomozygoteEarly adult1.2x10-5 
increased bone mineral content1 supporting datasetAbca2em1(IMPC)JhomozygoteEarly adult6.8x10-6 
increased circulating phosphate level1 supporting datasetAbca2em1(IMPC)JhomozygoteEarly adult2.99x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  










* This parameter was manually assessed for significance.
Download data as:  

lacZ Expression

Associated images

Loading...

Histopathology

IMPC related publications

Loading...

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Abca2em1(IMPC)JExon Deletionmouse
Abca2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Abca2tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

The IMPC Newsletter

Get highlights of the most important data releases, news and events, delivered straight to your email inbox

Subscribe to newsletter