Glp1r | glucagon-like peptide 1 receptor

GeneMGI:99571Synonyms: GLP1Rc, GLP-1R

Physiological systems

18 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Homeostasis/metabolism

17 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes



impaired glucose tolerance	2 supporting datasets	Glp1r^{tm1b(KOMP)Mbp}	homozygote	Early adult	1.04x10^-5
increased fasting circulating glucose level	1 supporting dataset	Glp1r^{tm1b(KOMP)Mbp}	homozygote	Early adult	8.48x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Glp1r.

Associated images

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Histopathology

There is no histopathology data found for Glp1r.

IMPC related publications

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External links

No external links available for Glp1r.

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*Glp1r^{tm1(NCOM)Mfgc}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Glp1r^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Glp1r^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Glp1r^{tm1c(KOMP)Mbp}*	Wild type floxed exon (post-Flp)	‌	mouse
*Glp1r^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	es cell

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