Pde4c | phosphodiesterase 4C, cAMP specific

GeneMGI:99556Synonyms: Dpde1, E130301F19Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

Behavior/neurological

16 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes



hyperactivity	4 supporting datasets	Pde4c^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	8.01x10^-5
decreased grip strength	2 supporting datasets	Pde4c^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	3.7x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pde4c.

Associated images

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Histopathology

There is no histopathology data found for Pde4c.

IMPC related publications

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External links

No external links available for Pde4c.

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*Pde4c^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Pde4c^{tm1.1(KOMP)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Pde4c^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pde4c^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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