Syk | spleen tyrosine kinase
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Adipose tissue Growth/size/body region Behavior/neurological Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | Syktm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased lean body mass | 1 supporting dataset | Syktm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.31x10-5 | ||
| decreased exploration in new environment | 1 supporting dataset | Syktm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.08x10-5 | ||
| increased total body fat amount | 1 supporting dataset | Syktm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.51x10-6 | ||
| decreased grip strength | 1 supporting dataset | Syktm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.29x10-5 |
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External links
No external links available for Syk.
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| Syktm1(EGFP_CreERT2)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Syktm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Syktm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Syktm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |