Tmsb4x | thymosin, beta 4, X chromosome

GeneMGI:99510Synonyms: Tb4, Ptmb4, +1 more

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Integument Behavior/neurological

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased thigmotaxis2 supporting datasetsTmsb4xem1(IMPC)MbphomozygoteEarly adult5.78x10-7 
abnormal behavior1 supporting datasetTmsb4xem1(IMPC)MbphomozygoteEarly adult8.59x10-7 
abnormal skin morphology1 supporting datasetTmsb4xem1(IMPC)MbphomozygoteEarly adultN/A * 
decreased locomotor activity1 supporting datasetTmsb4xem1(IMPC)MbphomozygoteEarly adult2.3x10-17 
decreased anxiety-related response1 supporting datasetTmsb4xem1(IMPC)MbphomozygoteEarly adult8.75x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tmsb4xem1(IMPC)MbpInter-exon deletionmouse
Tmsb4xtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Tmsb4xtm1(NCOM)CmhdReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Tmsb4xtm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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