Fgb | fibrinogen beta chain
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Hematopoietic system Cardiovascular system Mortality/aging
17 No significant impact
2 Not tested
Gene metrics:6Significant phenotypes
6Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues
| enlarged heart | 1 supporting dataset | Fgbtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| edema | 1 supporting dataset | Fgbtm1.1(KOMP)Vlcg | homozygote | E15.5 | N/A * | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Fgbtm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| impaired glucose tolerance | 1 supporting dataset | Fgbtm1.1(KOMP)Vlcg | homozygote | Early adult | 3.28x10-10 | ||
| edema | 1 supporting dataset | Fgbtm1.1(KOMP)Vlcg | heterozygote | E15.5 | N/A * | ||
| decreased circulating phosphate level | 1 supporting dataset | Fgbtm1.1(KOMP)Vlcg | heterozygote | Early adult | 9.96x10-5 | ||
| increased red blood cell distribution width | 1 supporting dataset | Fgbtm1.1(KOMP)Vlcg | homozygote | Early adult | 8.1x10-7 |
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External links
No external links available for Fgb.
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| Fgbtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Fgbtm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Fgbtm240578(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |