Arrb2 | arrestin, beta 2

GeneMGI:99474Synonyms: Arr3, beta-arrestin2, +3 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

47Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Arrb2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.33x10^-16
increased circulating cholesterol level	1 supporting dataset	Arrb2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	3.14x10^-6
increased grip strength	2 supporting datasets	Arrb2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	9.38x10^-6
increased circulating HDL cholesterol level	1 supporting dataset	Arrb2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	1.17x10^-6
increased circulating phosphate level	1 supporting dataset	Arrb2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	4.64x10^-5
increased circulating free fatty acids level	1 supporting dataset	Arrb2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.22x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arrb2.

Associated images

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Histopathology

There is no histopathology data found for Arrb2.

IMPC related publications

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External links

No external links available for Arrb2.

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*Arrb2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Arrb2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Arrb2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Arrb2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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