Arrb1 | arrestin, beta 1

GeneMGI:99473Synonyms: beta-arrestin1, 1200006I17Rik

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Growth/size/body region Hematopoietic system Cardiovascular system

14 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

50Embryo tissues

Phenotypes

Phy. System:



thrombocytopenia	1 supporting dataset	Arrb1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.44x10^-6
increased heart weight	1 supporting dataset	Arrb1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	7.1x10^-6
increased mean corpuscular hemoglobin	1 supporting dataset	Arrb1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.64x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Arrb1.

Associated images

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Histopathology

There is no histopathology data found for Arrb1.

IMPC related publications

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External links

No external links available for Arrb1.

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*Arrb1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Arrb1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Arrb1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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