Adora2b | adenosine A2b receptor
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Nervous system Vision/eye Behavior/neurological Cardiovascular system
12 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| decreased circulating glucose level | 1 supporting dataset | Adora2btm1.1(KOMP)Vlcg | homozygote | Early adult | 7.11x10-5 | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Adora2btm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.42x10-5 | ||
| convulsive seizures | 1 supporting dataset | Adora2btm1.1(KOMP)Vlcg | heterozygote | Early adult | 6.2x10-6 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Adora2btm1.1(KOMP)Vlcg | heterozygote | Early adult | 1.75x10-7 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Adora2btm1.1(KOMP)Vlcg | homozygote | Early adult | 2.09x10-9 |
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External links
No external links available for Adora2b.
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| Adora2btm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Adora2btm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Adora2btm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Adora2btm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |