Atp7a | ATPase, copper transporting, alpha polypeptide

GeneMGI:99400Synonyms: MNK, Menkes protein, +1 more

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Pigmentation Integument Behavior/neurological

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

7Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal coat/hair pigmentation	1 supporting dataset	Atp7a^em1(IMPC)J	hemizygote	Early adult	4.2x10^-12
abnormal coat/ hair morphology	1 supporting dataset	Atp7a^em1(IMPC)J	hemizygote	Late adult	1.99x10^-5
abnormal coat/hair pigmentation	1 supporting dataset	Atp7a^em1(IMPC)J	homozygote	Early adult	6.5x10^-12
abnormal vocalization	1 supporting dataset	Atp7a^em1(IMPC)J	hemizygote	Early adult	2.94x10^-10
abnormal vocalization	1 supporting dataset	Atp7a^em1(IMPC)J	homozygote	Early adult	2.42x10^-10

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Atp7a.

Associated images

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Histopathology

There is no histopathology data found for Atp7a.

IMPC related publications

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External links

No external links available for Atp7a.

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*Atp7a^em1(IMPC)J*	Exon Deletion	‌	mouse
*Atp7a^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Atp7a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Atp7a^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Atp7a^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Atp7a^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Atp7a^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Atp7a^{tm44904(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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