Pcgf2 | polycomb group ring finger 2

GeneMGI:99161Synonyms: Mel18, Zfp144, +2 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Hematopoietic system Skeleton Mortality/aging

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

1Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal testis morphology	1 supporting dataset	Pcgf2^{tm1b(KOMP)Mbp}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	3 supporting datasets	Pcgf2^{tm1b(KOMP)Mbp}	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Pcgf2^{tm1b(KOMP)Mbp}	heterozygote	Early adult	7.14x10^-5
small spleen	1 supporting dataset	Pcgf2^{tm1b(KOMP)Mbp}	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Pcgf2^{tm1b(KOMP)Mbp}	heterozygote	Early adult	N/A ^*
abnormal lumbar vertebrae morphology	1 supporting dataset	Pcgf2^{tm1b(KOMP)Mbp}	heterozygote	Early adult	2.67x10^-5
small testis	1 supporting dataset	Pcgf2^{tm1b(KOMP)Mbp}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pcgf2.

Associated images

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Histopathology

There is no histopathology data found for Pcgf2.

IMPC related publications

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External links

No external links available for Pcgf2.

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*Pcgf2^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pcgf2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Pcgf2^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pcgf2^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Pcgf2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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