Ezr | ezrin

GeneMGI:98931Synonyms: cytovillin, p81, +2 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, complete penetrance1 supporting datasetEzrtm2a(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal retina morphology1 supporting datasetEzrtm2a(EUCOMM)WtsiheterozygoteEarly adult7.71x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ezrtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ezrtm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Ezrtm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ezrtm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Ezrtm3e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Ezrtm4a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Ezrtm4e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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