Vil1 | villin 1

GeneMGI:98930Synonyms: Villin

Physiological systems

15 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system

11 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating fructosamine level1 supporting datasetVil1em1(IMPC)WtsihomozygoteEarly adult7.32x10-5 
decreased total body fat amount1 supporting datasetVil1em1(IMPC)WtsihomozygoteEarly adult1.98x10-5 
decreased circulating HDL cholesterol level1 supporting datasetVil1em1(IMPC)WtsihomozygoteEarly adult1.14x10-6 
increased red blood cell distribution width1 supporting datasetVil1em1(IMPC)WtsihomozygoteEarly adult3.2x10-5 
increased lean body mass1 supporting datasetVil1em1(IMPC)WtsihomozygoteEarly adult6.01x10-5 
decreased circulating cholesterol level1 supporting datasetVil1em1(IMPC)WtsihomozygoteEarly adult6.61x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Vil1em1(IMPC)WtsiDeletionmouse
Vil1tm1(EGFP_CreERT2)WtsiReporter-tagged deletion allele (with selection cassette)es cell
Vil1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Vil1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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