U2af1 | U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1
Physiological systems
18 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Pigmentation Integument Hearing/vestibular/ear Vision/eye Behavior/neurological Mortality/aging
12 No significant impact
6 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| irregularly shaped pupil | 1 supporting dataset | U2af1em1(IMPC)J | heterozygote | Early adult | 2.5x10-6 | ||
| increased grip strength | 1 supporting dataset | U2af1em1(IMPC)J | heterozygote | Early adult | 1.7x10-5 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | U2af1em1(IMPC)J | heterozygote | Early adult | 5.21x10-5 | ||
| abnormal auditory brainstem response | 3 supporting datasets | U2af1em1(IMPC)J | heterozygote | Early adult | 1.67x10-8 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | U2af1em1(IMPC)J | homozygote | E9.5 | N/A * | ||
| cornea opacity | 1 supporting dataset | U2af1em1(IMPC)J | heterozygote | Early adult | 2.84x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | U2af1em1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal coat/hair pigmentation | 2 supporting datasets | U2af1em1(IMPC)J | heterozygote | Early adult | 4.17x10-5 |
| | | | | | | | | | |
External links
No external links available for U2af1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| U2af1em1(IMPC)J | Exon Deletion | | mouse |
| U2af1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| U2af1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |