Tuba1a | tubulin, alpha 1A

GeneMGI:98869Synonyms: Tuba-1, Tuba1, +1 more

Physiological systems

16 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Mortality/aging Craniofacial Cardiovascular system

10 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

5Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:

Life Stage:



preweaning lethality, incomplete penetrance	3 supporting datasets	Tuba1a^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal embryo size	1 supporting dataset	Tuba1a^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
hemorrhage	1 supporting dataset	Tuba1a^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
abnormal facial morphology	1 supporting dataset	Tuba1a^em1(IMPC)Bay	homozygote	E18.5	N/A ^*
edema	1 supporting dataset	Tuba1a^em1(IMPC)Bay	homozygote	E18.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tuba1a.

Associated images

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Histopathology

There is no histopathology data found for Tuba1a.

IMPC related publications

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External links

No external links available for Tuba1a.

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*Tuba1a^em1(IMPC)Bay*	Inter-exon deletion	‌	mouse
*Tuba1a^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Tuba1a^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tuba1a^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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