Tnnc1 | troponin C, cardiac/slow skeletal
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Embryo Growth/size/body region Behavior/neurological Mortality/aging
16 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| prenatal lethality prior to heart atrial septation | 1 supporting dataset | Tnnc1em1(IMPC)J | homozygote | E15.5 | N/A * | ||
| limb grasping | 1 supporting dataset | Tnnc1em1(IMPC)J | heterozygote | Late adult | 9x10-5 | ||
| abnormal embryo size | 1 supporting dataset | Tnnc1em1(IMPC)J | heterozygote | E15.5 | N/A * | ||
| impaired righting response | 1 supporting dataset | Tnnc1em1(IMPC)J | heterozygote | Late adult | 2.35x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Tnnc1em1(IMPC)J | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Tnnc1em1(IMPC)J | homozygote | E12.5 | N/A * |
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External links
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| Tnnc1em1(IMPC)J | Exon Deletion | | mouse |
| Tnnc1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Tnnc1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |