Timp3 | tissue inhibitor of metalloproteinase 3

GeneMGI:98754Synonyms: Timp-3

Physiological systems

17 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Hematopoietic system Cardiovascular system

14 No significant impact

7 Not tested

Gene metrics:3Significant phenotypes
2Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues

Phenotypes

abnormal retina morphology1 supporting datasetTimp3tm1.1(KOMP)VlcghomozygoteEarly adult6.17x10-5 
increased mean corpuscular volume1 supporting datasetTimp3tm1.1(KOMP)VlcghomozygoteEarly adult1.71x10-5 
abnormal retina blood vessel morphology1 supporting datasetTimp3tm1.1(KOMP)VlcghomozygoteEarly adult2.86x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Timp3tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Timp3tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Timp3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Timp3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Timp3tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Timp3tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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