Timp1 | tissue inhibitor of metalloproteinase 1

GeneMGI:98752Synonyms: TIMP-1, Clgi

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Limbs/digits/tail Skeleton

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:92Adult tissues

63Embryo tissues

Phenotypes

Phy. System:



abnormal femur morphology	1 supporting dataset	Timp1^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	2.47x10^-9
abnormal humerus morphology	1 supporting dataset	Timp1^{tm1b(EUCOMM)Hmgu}	hemizygote	Early adult	3.53x10^-11

* Does not have a P-value assigned because it was manually marked as significant.

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* Does not have a P-value assigned because it was manually marked as significant.

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lacZ Expression

No adult expression data available for Timp1.

Associated images

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Histopathology

There is no histopathology data found for Timp1.

IMPC related publications

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External links

No external links available for Timp1.

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*Timp1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Timp1^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Timp1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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