Thbs2 | thrombospondin 2

GeneMGI:98738Synonyms: TSP2, Thbs-2, +1 more

Physiological systems

20 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Reproductive system Immune system Integument Endocrine/exocrine gland Growth/size/body region Vision/eye Hematopoietic system Renal/urinary system

12 No significant impact

4 Not tested

Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology2 supporting datasetsThbs2em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged prostate gland1 supporting datasetThbs2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal vitreous body morphology1 supporting datasetThbs2em1(IMPC)MbphomozygoteEarly adult5.99x10-5 
cataract1 supporting datasetThbs2em1(IMPC)MbphomozygoteEarly adult6.35x10-5 
enlarged spleen1 supporting datasetThbs2em1(IMPC)MbphomozygoteEarly adultN/A * 
small kidney1 supporting datasetThbs2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal kidney morphology1 supporting datasetThbs2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetThbs2em1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal prostate gland morphology1 supporting datasetThbs2em1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Thbs2em1(IMPC)MbpExon Deletionmouse
Thbs2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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