Tgfbr2 | transforming growth factor, beta receptor II

GeneMGI:98729Synonyms: TbetaR-II, TbetaRII, +2 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Growth/size/body region Liver/biliary system Cardiovascular system Mortality/aging Renal/urinary system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

8Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal heart morphology	1 supporting dataset	Tgfbr2^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*
small liver	1 supporting dataset	Tgfbr2^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Tgfbr2^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Tgfbr2^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Tgfbr2^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Tgfbr2^{em1(IMPC)Rbrc}	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Tgfbr2^{em1(IMPC)Rbrc}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tgfbr2.

Associated images

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Histopathology

There is no histopathology data found for Tgfbr2.

IMPC related publications

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External links

No external links available for Tgfbr2.

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*Tgfbr2^{em1(IMPC)Rbrc}*	Exon Deletion	‌	mouse
*Tgfbr2^{tm189785(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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