Tgfb3 | transforming growth factor, beta 3
Physiological systems
20 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Reproductive system Immune system Endocrine/exocrine gland Mortality/aging
16 No significant impact
4 Not tested
Gene metrics:3Significant phenotypes
7Associated diseases
Expression examined in:41Adult tissues
29Embryo tissues
| preweaning lethality, complete penetrance | 2 supporting datasets | Tgfb3tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Tgfb3tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * | ||
| abnormal testis morphology | 1 supporting dataset | Tgfb3tm1.1(KOMP)Vlcg | heterozygote | Early adult | N/A * |
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External links
No external links available for Tgfb3.
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| Tgfb3tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
| Tgfb3tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Tgfb3tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Tgfb3tm449986(L1L2_Bact_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |