Tcf4 | transcription factor 4

GeneMGI:98506Synonyms: SEF-2, E2-2, +11 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

6Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina morphology	1 supporting dataset	Tcf4^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.58x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Tcf4^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Tcf4.

Associated images

Loading...

Histopathology

There is no histopathology data found for Tcf4.

IMPC related publications

Loading...

External links

No external links available for Tcf4.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Tcf4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Tcf4^{tm1c(EUCOMM)Wtsi}*	Wild type floxed exon (post-Flp)	‌	mouse
*Tcf4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell

My Genes