Syp | synaptophysin

GeneMGI:98467Synonyms: Syp I, Syn, +2 more

Physiological systems

10 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

8 No significant impact

14 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased vertical activity1 supporting datasetSypem1(IMPC)BayhemizygoteEarly adult8.04x10-7 
preweaning lethality, incomplete penetrance1 supporting datasetSypem1(IMPC)BayhomozygoteEarly adultN/A * 
increased vertical activity1 supporting datasetSypem1(IMPC)BayheterozygoteEarly adult1.39x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Sypem1(IMPC)BayExon Deletionmouse
Syptm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Syptm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Syptm40672(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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