Shmt1 | serine hydroxymethyltransferase 1 (soluble)

GeneMGI:98299Synonyms: Shmt, mshmt1, +2 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



increased mean platelet volume	1 supporting dataset	Shmt1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.16x10^-6
increased circulating amylase level	1 supporting dataset	Shmt1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.2x10^-31

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Shmt1.

Associated images

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Histopathology

There is no histopathology data found for Shmt1.

IMPC related publications

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External links

No external links available for Shmt1.

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*Shmt1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Shmt1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Shmt1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell

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